Our third paper on the chemical origins of life is published in Nature. We show that ferrous iron promotes a one-pot reaction network that resembles the Krebs cycle and amino acid synthesis, starting from just pyruvate and glyoxylate. These enzyme-free reactions could have been a precursor to biological metabolism. Congrats to Kamila and Sreejith! Free read-only version here. Paywall version here. Also, check out the accompanying News & Views article by Robert Pascal here.