New publication

Ed, Jing and Vuk’s paper in Chemical Science shows that hexafluoroisopropanol solvent enables simple monosubstituted cyclopropanes to undergo ring-opening hydroarylation – no donor-acceptor motif required. A good chunk of this work came from Jing’s M2 internship in our group. Special thanks to the Rowley group from Memorial University in Canada for the DFT calculations. Congrats to all!

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New publication

Our second paper on the chemical origins of life is published in Nature Ecology & Evolution. We show that metallic iron powder fixes carbon dioxide as acetate and pyruvate much like the Acetyl CoA pathway, an ancient biological pathway used by microbes to build themselves. It represents a rare “chemistry-up” experiment that connects with the current “biology-down” understanding of early life. Congrats to Sreejith, Kamila and Paul! Free read-only version here. Paywall version here. Also check out the accompanying Behind the Paper post here.

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New publication

Ed and Vuk’s paper on the accelerating effect of HFIP solvent on nucleophilic ring-opening of donor-acceptor cyclopropanes has been published in Organic Letters. Congrats!

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New publication

Our paper on the chemical origins of life is published in Nature Ecology & Evolution. We show that more than half of the reverse Krebs cycle can occur without enzymes. Congrats to Kamila, Sreejith, Elodie, Lucas and Guang for an amazing team effort! A free link to the paper is here. The journal’s paywall version is here. Also check out our Behind the Paper blog post on the journal’s web site here.

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New publication

Vuk, Ed and Eléna’s article on HFIP-assisted dehydrative Friedel-Crafts reactions of highly deactivated benzylic alcohols has been accepted for publication in Angewandte Chemie International Edition. It is Vuk’s first paper from his PhD and Eléna’s last. Congrats!

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New publication

Marian, Ed and Guang’s article on catalytic substitution of alkyl fluorides has been published in Journal of Fluorine Chemistry. Special congrats to Guang, who did a large part of this work during his M1 stage.toc

New Publication

Our first paper from our collaboration with the Ebbesen group describing how strong coupling to the vacuum field can be exploited to change the rate of chemical reactions has been accepted for publication in Angewandte Chemie. Congrats to all who participated from the Ebbesen group and to Marian and Sreejith from our group!

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